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juillet 2025<\/strong><\/h4>\n

Nexavar (soraf\u00e9nib): Risque de syndrome de lyse tumorale (SLT) <\/strong><\/h4>\n

Des cas de SLT, certains ayant \u00e9t\u00e9 mortels, ont \u00e9t\u00e9 signal\u00e9s dans le cadre de la pharmacovigilance chez des patients trait\u00e9s par le soraf\u00e9nib.<\/p>\n

Les facteurs de risque de SLT sont les suivants : fardeau tumoral \u00e9lev\u00e9, insuffisance r\u00e9nale chronique pr\u00e9existante, oligurie, d\u00e9shydratation, hypotension et urine acide.<\/p>\n

Les patients doivent \u00eatre suivis de pr\u00e8s et trait\u00e9s rapidement si le tableau clinique le justifie. Des mesures prophylactiques seront envisag\u00e9es si cela est indiqu\u00e9 sur le plan clinique.<\/p>\n

Plus de renseignements: <\/strong><\/p>\n

InfoVigilance sur les produits de sant\u00e9<\/strong><\/a><\/span>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

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